Article got my attention. What I've seen is a battle between confused B-amyloid (majority) and Tau (growing minority) scientists who are struggling to come to terms with the fact that both plaques and tangles are associated with Alzheimer's (AD)... And the plaque folks took a small blow when the drug Alzamed came plowing through as the hero drug of the day starting back around 2004... It stops the b-amyloid from clumping together into plaques. Ready to report a breakthrough at the annual AD conference in 2007... and all the news stations said "tomorrow we may show you the cure for AD!" The day of the conference the alzamed people proudly marched in and reported insignificant findings... Lamo.
Sorry for the tangent, but seems like a good back-story. Anyway, I'm skeptical of the insulin theory. In my mind, this seems a lot like another masking, another treatment, another boost that hides the effects. Cognitive reserve does that (being strong means you can do more even if your wrist is sprained)...
Seems more like a result of damaged neurons is decreased glucose metabolism.
All that said, I'm gonna read the Neurology paper and see what the scoop is.
Feel free to change the site's appearance as you like. With a wiki style, it can end up however we like. Also, invite anyone you think will post good articles and/or contribute to the commentary.
Notes
3/25/09 Eric: Dave, site changes look awesome. I made some more.
3/25/09 Jess: I have access to online Nature. Will post or email pdf or something.
Requests
3/26/09 Eric: Frequently updated and interesting blogs. Any recommendations? (add below to News Sites)
Article got my attention. What I've seen is a battle between confused B-amyloid (majority) and Tau (growing minority) scientists who are struggling to come to terms with the fact that both plaques and tangles are associated with Alzheimer's (AD)... And the plaque folks took a small blow when the drug Alzamed came plowing through as the hero drug of the day starting back around 2004... It stops the b-amyloid from clumping together into plaques. Ready to report a breakthrough at the annual AD conference in 2007... and all the news stations said "tomorrow we may show you the cure for AD!" The day of the conference the alzamed people proudly marched in and reported insignificant findings... Lamo.
ReplyDeleteSorry for the tangent, but seems like a good back-story. Anyway, I'm skeptical of the insulin theory. In my mind, this seems a lot like another masking, another treatment, another boost that hides the effects. Cognitive reserve does that (being strong means you can do more even if your wrist is sprained)...
Seems more like a result of damaged neurons is decreased glucose metabolism.
All that said, I'm gonna read the Neurology paper and see what the scoop is.